El ibuprofeno es eficaz en el cierre del conducto arterioso persistente en el recién nacido pretérmino y presenta menos efectos secundarios que la indometacina
- Andrés de Llano, Jesús María
- Ochoa Sangrador, Carlos
ISSN: 1885-7388
Ano de publicación: 2010
Volume: 6
Número: 2
Tipo: Artigo
Outras publicacións en: Evidencias en pediatría
Resumo
Authors� conclusions: Ibuprofen is effective in closing a patent ductus arteriosus. Ibuprofen is as effective as indomethacin in closing a ductus and reduces the risk of necrotizing enterocolitis and transient renal insufficiency. Ibuprofen could be the drug of choice, although studies are needed to evaluate the effect of the Ibuprofen treatment compared to indomethacin on long-term outcomes. Reviewers� commentary: the use of ibuprofen seems to be safe and effective in closing a ductus with fewer side effects than indomethacin. Studies with more number of patients are needed to evaluate the effect on long-term outcomes.