Factores clínicos de riesgo para el desarrollo de la vitreorretinopatía proliferante (VRP) postquirúrgicaEstudio prospectivo

  1. E Rodríguez de la Rúa
  2. V Martínez
  3. J Aragón
  4. RM Sanabria
  5. A Giraldo
  6. A Mayo
  7. JC Pastor
  8. I Miranda
  9. J García Arumí
Journal:
Archivos de la Sociedad Española de Oftalmologia

ISSN: 0365-6691

Year of publication: 2003

Volume: 78

Issue: 2

Pages: 91-97

Type: Article

DOI: 10.4321/S0365-66912003000200005 DIALNET GOOGLE SCHOLAR lock_openOpen access editor

More publications in: Archivos de la Sociedad Española de Oftalmologia

Abstract

Purpose: To identify clinical risk factors for development of postoperative PVR, to determine the incidence of this complication and its time of onset by a prospective multicentric study. Methods: A multicentric and prospective study of 223 patients with rhegmatogenous retinal detachment (RD) was conducted. Logistic regression analysis was used to identify risk factors for PVR among 83 variables related to preoperative, intraoperative and postoperative characteristics. Results: 22 out of 223 RD developed PVR (incidence 9.9%, confidence interval 95%: 5.9-13.9). After logistic regression analysis, four variables showed an odds ratio higher than 1.0 (RD affecting 4 quadrants, cryopexy, aphakia/pseudophakia and those RD in which an encircling band was implanted). None of these factors showed a «p» value lower than 0.05. Most of postoperative PVR (77.2%) appeared in the first month after surgery. Conclusions: This study establishes the incidence of PVR, and its time of onset, but it was not effective to identify clinical risk factors with a high level of confidence.

Bibliographic References

  • Pastor, JC. (1998). Proliferative vitreoretinopathy: an overview. Surv Ophthalmol. 43. 3-18
  • Lleó Pérez, A, Campos Fernández, R, López Santoveña, F, Sánchez Llorente, G, Hernández Martínez, FJ, Navarro Palop, C. (2000). Factores clínicos de riesgo de la vitreorretinopatía proliferativa después de la cirugía del desprendimiento de retina. Arch Soc Esp Oftalmol. 75. 741-750
  • Martín Ruiz, E, Moreno Guerrero, A, Tirado Carmona, A, Rius Díaz, F, García Campos, JM. (2000). Complicaciones de la cirugía del desprendimiento de retina. Arch Soc Esp Oftalmol. 75. 371-376
  • Bonnet, M, Guenoun, S. (1995). Surgical risk factors for severe postoperative proliferative vitreoretinopathy (PVR) in retinal detachment with grade B PVR. Graefe's Arch Clin Ophthalmol. 233. 789-791
  • Kon, CH, Asaria, RH, Occleston, NL, Khaw, PT, Aylward, GW. (2000). Risk factors for proliferative vitreoretinopathy after primary vitrectomy: a prospective study. Br J Ophthalmol. 506-511
  • Girard, P, Mimoun, G, Karpouzas, I, Montefiore, G. (1994). Clinical risk factors for proliferative vitreoretinopathy after retinal detachment surgery. Retina. 14. 417-424
  • Nagasaki, H, Shinagawa, K, Mochizuki, M. (1998). Risk factors for proliferative vitreoretinopathy. Prog Retin Eye Res. 17. 77-98
  • Yoshino, Y, Ideta, H, Nagasaki, H, Uemura, A. (1989). Comparative study of clinical factors predisposing patients to proliferative vitreoretinopathy. Retina. 9. 97-100
  • Malbran, E, Dodds, RA, Hulsbus, R, Charles, DE, Buonsanti, JL, Adrogué, E. (1990). Retinal break type and proliferative vitreoretinopathy in nontraumatic retinal detachment. Graefes Arch Clin Exp Ophthalmol. 228. 423-425
  • Rodríguez de la Rúa, E, Aragón, JA, Pastor, JC, Carrasco, B, González, JC, Álvarez-Requejo. (2000). Posibilidad de predecir el riesgo de una vitreorretinopatía proliferante mediante el análisis de factores clínicos de los desprendimientos de retina regmatógenos. Arch Soc Esp Oftalmol. 75. 807-812
  • (1983). The classification of retinal detachment with proliferative vitreoretinopathy. Ophthalmology. 90. 121-125
  • Aguirrebeña, A, Saornil, MA, Giraldo, A, Pastor, JC. (1986). Incidencia de la vitreorretinopatía proliferante (VRP) en el desprendimiento de retina regmatógeno. Arch Soc Esp Oftalmol. 51. 229-234
  • Bonnet, M, Fleury, J, Guenoun, S, Yaniali, A, Dumas, C, Hajjar, C. (1996). Cryopexy in primary rhegmatogenous retinal detachment: a risk factor for postoperative proliferative vitreoretinopathy?. Graefes Arch Clin Exp Ophthalmol. 234. 739-743
  • Duquesne, N, Bonnet, M, Adeleine, P. (1996). Preoperative vitreous hemorrhage associated with rhegmatogenous retinal detachment: a risk factor for postoperative proliferative vitreoretinopathy?. Graefes Arch Clin Exp Ophthalmol. 234. 677-682
  • Mietz, H, Heimann, K. (1995). Onset and recurrence of proliferative vitreoretinopathy in various vitreoretinal diseases. Br J Ophthalmol. 79. 874-877