Resultados a corto y largo plazo tras tratamientos curativos del hepatocarcinoma en una población de gran dispersión geográfica

Abstract

OBJECTIVE: To analyze whether patients in Extremadura affected by hepatocellular carcinoma (HCC) subsidiary of potentially curative treatments (resection [LR], transplant [LT] and radiofrequency [RF]) receive the same therapeutic management regardless of their origin and evaluate short/long term results of these treatments. MATERIAL AND METHODS: Retrospective analysis between January 2007 to December 2015, dividing the patients into the Badajoz health area (BHA) and the other health areas (OHA), analyzing the period from diagnosis to presentation to the committee and treatment, as well as evaluating immediate postoperative death (IPD), overall survival (OS), recurrence and disease-free survival (DFS) of each modality. RESULTS: There are no differences between BHA/OHA in period until committee presentation in patients undergoing HR (18vs20 days, p = 0.85), LT (26/31 days, p = 0.63) and RF (21/26 days, p = 0,22); there is also no difference in time to main treatment in HR (69/77 days, p = 0,63), LT (104/97 days, p = 0,76) and RF (125/97 days, p = 0,49). The IPD, OS at five years, recurrence and DFS at five years is in HR is 5,4%, 46,4%, 57,7% and 29,9%, respectively; in LT of 7,2%, 65,2%, 12,5% and 85,6%, respectively; and in RF of 4,9%, 33,2%, 64,1% and 14,7%, respectively. CONCLUSIONS: All patients with potentially curative HCC have the same management, both temporal and therapeutic, regardless of the area of origin. Likewise, the short and long-term results with the different curative treatments are in accordance with the different studies published in the literature.