Studio ultraestructural de los efectos de las drogas de adicción a nivel del hígadoEstudio experimental

  1. Vaquero, Ana
  2. Agudo, J.
  3. Gil Verona, José Antonio
  4. Diago Santamaría, María Victoria
  5. San Norberto García, Enrique
  6. Vaquero Puerta, Carlos
Revista:
Revista española de investigaciones quirúrgicas

ISSN: 1139-8264

Año de publicación: 2012

Volumen: 15

Número: 4

Páginas: 192-196

Tipo: Artículo

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Otras publicaciones en: Revista española de investigaciones quirúrgicas

Resumen

Drugs abusers are frequently found to have abnormal liver function tests and hepatic histology. The aim of the present work was to analyse, at the ultrastructural level, the action of drugs abuse in the liver mice. Liver injury was induced by a repetitive dose of cocaine, ecstasy and heroin in male albino Swiss mice during 21 days. There has been an ultrastructural study, after processing of the liver samples treated by different drugs given to animals integrated into different groups. The results are shown different level of intracellular organelle structures and changes induced by the administration of different drugs. It attempts to correlate ultrastructural changes with repercussions from the physiological point of view and its clinical consequences in humans.

Fuente de los datos: Dialnet