Metástasis intraocular como presentación sistémica de un adenocarcinoma de próstata con diferenciación neuroendocrina

  1. F.J. Valentín Bravo 1
  2. M.A. Saornil Álvarez 1
  3. C. García Álvarez 1
  4. E. García Lagarto 1
  5. R. López Castro 1
  1. 1 Hospital Universitario de Valladolid

    Hospital Universitario de Valladolid

    Valladolid, España


Archivos de la Sociedad Española de Oftalmologia

ISSN: 0365-6691

Year of publication: 2021

Volume: 96

Issue: 6

Pages: 332-336

Type: Article


More publications in: Archivos de la Sociedad Española de Oftalmologia


A 68 year-old male was referred for assessment of an amelanotic lesion in the right eye (RE) that was associated with a gradual loss of visual acuity (VA), of 2 months onset, as the main symptom. It was noted in his medical history, that 6 years ago, he had prostate cancer treated with prostatectomy, lymphadenectomy, and coadjuvant local radiotherapy (RT). He was asymptomatic until 6 months ago, when a metastasis was discovered in the left femur, which was treated with radiotherapy. There were no findings of interest in the left eye (LE). His VA was very low in his RE, and in the eye fundus examination a mass without pigment was observed in the posterior pole with an adjacent exudative retinal detachment. Due to his personal history and results of the complementary tests such as ultrasound and magnetic resonance, the most likely diagnostic option was metastasis of prostate carcinoma, subsequently being confirmed with the histopathology results. Despite 4 cycles of chemotherapy, the patient did not show any clinical or radiological response, worsening until his death 3 months later.