Distribution in tissues and effects by acute hypoxia on angiotensin I converting enzyme activity in guinea pig and chicken
- C. Cuadrillero
- M. J. Polanco
- Maria Teresa Agapito Serrano
- J. M. Recio
ISSN: 0034-9402
Año de publicación: 1984
Volumen: 40
Número: 3
Páginas: 371-374
Tipo: Artículo
Otras publicaciones en: Revista española de Fisiología
Resumen
Angiotensin I converting enzyme activity was measured in homogenates of guinea pig and chicken organs (lung, kidney, heart, ileum, diaphragm and liver), using a spectrophotometric assay for hydrolysis of hippuryl-L-histidyl-L-leucine. High specific activities were found in lung, kidney and diaphragm, but the highest corresponded to guinea pig lung and chicken kidney. Acute hypoxia decreased angiotensin I converting enzyme activity in guinea pig lung and chicken diaphragm, but the changes in kidney were considered non-significant in both the guinea pig and chicken.