Circular Isotone Regression with Application to cell-cycle Biology

1. Rueda Sabater, María Cristina
2. Fernández Temprano, Miguel Alejandro
3. Barragán, Sandra
4. Mardia, Kanti
5. Peddada, Shyamal

Exportar

Exportar

×

MLA

modern-language-association

APA

apa

Chicago

chicago-fullnote-bibliography

Harvard

harvard-cite-them-right

Vancouver

vancouver-author-date

---

RIS BibTex

Exportar

×

El documento no se puede exportar porque pertenece a otro portal.

Texto completo

lock_openUVADOC externo lock_openUVADOC externo

GOOGLE SCHOLAR lock_openUVADOC editor

Resumen

This work is motivated by a problem encountered in Molecular Biology where researchers are interested in correlating angular data from two oscillatory systems. The observations are the time to peak expression (also known as phase angle) of periodic genes under two different conditions (dose levels, organs or even species). In particular, we deal here with expression data from genes participating in the cell-cycle. Cell-biologists are often interested in drawing inferences regarding the phase angle of cell-cycle genes since they are considered to be associated with the gene’s biological function (Jensen et al 2006).