ChemInform Abstract: In situ Generation of ArCu from CuF<sub>2</sub>Makes Coupling of Bulky Aryl Silanes Feasible and Highly Efficient.
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Universidad de Valladolid
info
ISSN: 0931-7597
Año de publicación: 2016
Volumen: 47
Número: 31
Tipo: Artículo
Otras publicaciones en: ChemInform
Resumen
A bimetallic system of Pd/CuF2, catalytic in Pd and stoichiometric in Cu, is efficient and selective for the coupling of fairly hindered aryl silanes with aryl iodides of conventional size. The reaction involves the activation of the silane by Cu(II), followed by disproportionation and transmetalation from the Cu(I)(aryl) to Pd(II), upon which coupling takes place. Cu(III) formed during disproportionation is reduced to Cu(I)(aryl) by excess aryl silane, so that the CuF2 system is fully converted into Cu(I)(aryl) and used in the coupling. No extra source of fluoride is needed. Interesting size selectivity towards coupling is found in competitive reactions of hindered aryl silanes. The isolated products are essentially free from As or Pd.
Referencias bibliográficas
- delPozo, (2016), Chem. - Eur. J., 22, pp. 4274, 10.1002/chem.201504435