Elastin-Like Polymers: Properties, Synthesis, and Applications

  1. Rodriguez-Cabello, J. Carlos 1
  2. Ibáñez Fonseca, Arturo 1
  3. Alonso, Matilde 1
  4. Poocza, Leander 1
  5. Cipriani, Filippo 2
  6. González de Torre, Israel 12
  1. 1 Bioforge; Universidad de Valladolid; Valladolid Spain
  2. 2 Technical Proteins NanoBiotechnology; Valladolid Spain
Libro:
Encyclopedia of Polymer Science and Technology

Año de publicación: 2017

Páginas: 1-36

Tipo: Capítulo de Libro

DOI: 10.1002/0471440264.PST656 GOOGLE SCHOLAR lock_openAcceso abierto editor

Resumen

Elastin-like recombinamers (ELRs) are biological polymers that due to their flexibility in the design, their self-assembly properties, easy chemical modification allowing the introduction of many interesting functionalities, versatility to be processed in many forms (aggregates, fibers, layers, nanoparticles, or hydrogels), and excellent cyto- and biocompatibility have great potential in many fields, including drug delivery, tissue engineering, protein purification, anticancer gene therapies, and nanovaccines. In the next pages, we explore the evolution of ELRs from their ancient chemical origin to the most cutting-edge bioproduction techniques, exploring several hosts that can be used to bioproduce them and their design versatility. We will also discuss several structures formed by ELRs and their potential medical applications.

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