Estudio del efecto del Cardiazol y algunos fármacos antiepilépticos sobre la actividad ATPasa y consumo de oxígeno asociado en cerebro de rata in vitro

  1. Ana María Rubio Pérez 1
  2. José Luis García Roldan 1
  3. José Luis González Martínez De Zarate 1
  4. Alfonso Velasco Martín 1
  1. 1 Universidad de Valladolid

    Universidad de Valladolid

    Valladolid, España


Revista de toxicología

ISSN: 0212-7113

Year of publication: 1987

Volume: 4

Issue: 1

Pages: 45-53

Type: Article

More publications in: Revista de toxicología

Bibliographic References

  • AKERA, T., and BRODY, T. M.: The Role of Na+ - K+ - ATPase in the inotropic action of Digitalis. Pharmacol. Rev., 29: (3) 192-219, 1978.
  • AKERA, T.; GUBITZ, R. H.; BRODY, T. M., y TOBIN, T.: Effects of monovalentcations on (Na+ - K+) - ATPase in rat brain slices. Eur. J. Pharmacoloay, 55-(2/3)281-289,1979.
  • AREVALO, P.: Efectos de algunos fármacos antidepresivos tricíclicos sobre la actividad ATPasa y consumo de oxígeno asociado en cerebro de rata in vitro. Tesis doctoral. Facultad de Veterinaria. Universidad Complutense, Madrid 1983
  • DELGADO-ESCUELA, A., and HORAN, M. P.: Brain synaptosomen in Epilepsy: Organization of ionic channels and the Na+ - K+ pump, en Antiepileptic drugs mechanisms of action (Gilberts, H. G.; Kiffin, J., and Woodbury, D., eds ) Raven Press. New York, 85-126, 1980.
  • FESTOFF, B. W., and APPEL, S. H.: Effect of phenytoin on synaptosome sodiumpotasium-ATPase. J. Clin. Invest., 47: (11), 2752-2758, 1968.
  • GILBERT, J. C; GRAY, P., and HEATON, G. W.: Anticonvulsant drugs and brain glucose. Biochem. Pharmac. 20: (2) 240-243, 1971.
  • GROSS, G. J. and WOODBURY, D. M.: Effects of pentylenetetrazol on ion transpon in the isolated toad bladder. J. Pharmacol. Exp. ther. 181: (2) 257-272 1972
  • GUBITZ, R. H.; AKERA, T., and BRODY, T. M.: Control of brain slices respiration by (Na+ - K+) activates adenosine triphosphates and the effect of enzyme inhibitors. Biochim. Biophys. Acta, 459: (2) 263-277, 1977.
  • HERTZ, L., and SCHOU, M.: Univalent cations and the respiration of brain slices Biochem., J., 85: (1) 93-102, 1962.
  • MclLWAIN, H., and BUDDLE, A. L.: Techniques in tissue metabolism A Mechanical Chopper. Biochem. J. 53: (3) 412-420, 1953.
  • NAHORSKI, S. R.: Biochemical effects of the anticonvulsants trimethadione ethosuximide and chlordiazepoxide in rat brain. J. Neurochem., 19: (12) ig37-1946 1972.
  • OLSEN, R. W.: GABA-benzodiazepine-barbiturate receptor interactions. J. Neurochem. 37: (1) 1-13, 1981.
  • RAWSON, M. D., and PINCUS, J. H.: The effect of diphenylhydantoin on sodium potassium magnesium activated adenosine triphosfatase in microsomal fractions of rat and guinea pig brain and on whole homogenates of human brain. Biochem. Pharmacol., 17: (4) 573-579, 1968.
  • SCHWARTZ, A.; LINDENMAYER, G. E., and ALLEN,J. O: The sodium-potassium adenosine triphosphatase: pharmacological, physiological and biochemical aspects. Pharmacol. Rev., 27: (1) 1-134, 1975.
  • UMBREIT, W. W.; BURRIS, R. H., and STAUFFER, J. F.: Manometric and Biochemical Techniques, Burgess Publishing Co. 5th Minneapolis, 1972.
  • WHITE, W. F.; DICHTER, M. A., and SNODGRASS, S. R.: Benzodiazepine binding and interactions with the GABA receptor complex in living cultures of rat cerebral cortex. Brain Res., 215: (1) 162-176, 1981.
  • WHITTAM, R., y BLOND, D. M.: Respiration control by adenosine triphosphatase involved in active transpon in brain cortex. Biochem. J., 92 (2) 147-151, 1964.
  • WU, P. H., and PHILLIS, J. W.: Methergoline antagonism of 5 hydroxy tryptamine-induced activation of rat cerebral cortical (Na-K) ATPasa. J. Pharm. Pharmacol., 31: (11) 780-782, 1979.