DAVID JOSE
SANZ SAN JOSE
PROFESORA SUSTITUTA/PROFESOR SUSTITUTO
Publications (21) DAVID JOSE SANZ SAN JOSE publications
2023
-
Molecular and functional correction of a deep intronic splicing mutation in CFTR by CRISPR-Cas9 gene editing
Molecular Therapy - Methods and Clinical Development, Vol. 31
-
Use of adenine base editing and homology-independent targeted integration strategies to correct the cystic fibrosis causing variant, W1282X
Human molecular genetics, Vol. 32, Núm. 23, pp. 3237-3248
2022
-
Comparison of Cas9 and Cas12a CRISPR editing methods to correct the W1282X-CFTR mutation
Journal of Cystic Fibrosis, Vol. 21, Núm. 1, pp. 181-187
2019
-
Minigene Assay to Evaluate CRISPR/Cas9-based Excision of Intronic Mutations that Cause Aberrant Splicing in Human Cells
Bio-protocol, Vol. 9, Núm. 11
2018
-
Gene Editing of Stem Cells to Model and Treat Disease
Current Stem Cell Reports, Vol. 4, Núm. 3, pp. 253-263
2017
-
Cas9/gRNA targeted excision of cystic fibrosis-causing deep-intronic splicing mutations restores normal splicing of CFTR mRNA
PLoS ONE, Vol. 12, Núm. 9
-
Functional classification of DNA variants by hybrid minigenes: Identification of 30 spliceogenic variants of BRCA2 exons 17 and 18
PLoS Genetics, Vol. 13, Núm. 3
2016
-
Impact of gene editing on the study of cystic fibrosis
Human Genetics, Vol. 135, Núm. 9, pp. 983-992
-
Toxicity and genotoxicity of metal and metal oxide nanomaterials: A general introduction
Handbook of Clinical Nanomedicine: Law, Business, Regulation, Safety, and Risk (Pan Stanford Publishing Pte. Ltd.), pp. 901-929
2014
-
Potential impact of metal oxide nanoparticles on the immune system: The role of integrins, L-selectin and the chemokine receptor CXCR4
Nanomedicine: Nanotechnology, Biology, and Medicine, Vol. 10, Núm. 6, pp. 1301-1310
-
Toxicity and genotoxicity of metal and metal oxide nanomaterials: A general introduction
Horizons in Clinical Nanomedicine (Pan Stanford Publishing Pte. Ltd.), pp. 289-316
2013
-
Layer by layer surface engineering of poly (lactide-co-glycolide) nanoparticles: A versatile tool for nanoparticle engineering for targeted drug delivery
Science China Chemistry, Vol. 56, Núm. 8, pp. 1029-1039
-
Lipid layer engineering of poly(lactide-co-glycolide) nanoparticles to control their uptake and intracellular co-localisation
Journal of Materials Chemistry B, Vol. 1, Núm. 17, pp. 2252-2259
-
Poly(Lactide-co-Glycolide) Nanoparticles, Layer by Layer Engineered for the Sustainable Delivery of AntiTNF-α
Macromolecular Bioscience, Vol. 13, Núm. 7, pp. 903-912
2012
-
Comprehensive splicing functional analysis of DNA variants of the BRCA2 gene by hybrid minigenes
Breast Cancer Research, Vol. 14, Núm. 3
2011
-
Stepwise surface tailoring of carbon nanotubes with polyelectrolyte brushes and lipid layers to control their intracellular distribution and "in vitro" toxicity
Soft Matter, Vol. 7, Núm. 15, pp. 6883-6890
2010
-
A high proportion of DNA variants of BRCA1 and BRCA2 is associated with aberrant splicing in breast/ovarian cancer patients
Clinical Cancer Research, Vol. 16, Núm. 6, pp. 1957-1967
-
BRCA1 5272-1G>A and BRCA2 5374delTATG are founder mutations of high relevance for genetic counselling in breast/ovarian cancer families of Spanish origin
Clinical Genetics, Vol. 77, Núm. 1, pp. 60-69
-
Two founder BRCA2 mutations predispose to breast cancer in young women
Breast Cancer Research and Treatment, Vol. 122, Núm. 2, pp. 567-571
2009
-
A new strategy to screen MMR genes in Lynch Syndrome: HA-CAE, MLPA and RT-PCR
European Journal of Cancer, Vol. 45, Núm. 8, pp. 1485-1493