Publications (61) IRENE COZAR CASTELLANO publications

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2025

  1. Decreased expression of insulin-degrading enzyme increases gluconeogenesis and glucose production in cultured hepatocytes administered with glucagon

    Scientific Reports, Vol. 15, Núm. 1

  2. Hyperglucagonemia and glucagon hypersecretion in early type 2 diabetes result from multifaceted dysregulation of pancreatic mouse α-cells

    Pflugers Archiv European Journal of Physiology, Vol. 477, Núm. 2, pp. 207-221

2024

  1. Correction to: Insulin-degrading enzyme ablation in mouse pancreatic alpha cells triggers cell proliferation, hyperplasia and glucagon secretion dysregulation (Diabetologia, (2022), 65, 8, (1375-1389), 10.1007/s00125-022-05729-y)

    Diabetologia

  2. β2-Chimaerin, a GTPase-Activating Protein for Rac1, Is a Novel Regulator of Hepatic Insulin Signaling and Glucose Metabolism

    Molecules, Vol. 29, Núm. 22

2023

  1. Insulin-degrading enzyme (IDE) as a modulator of microglial phenotypes in the context of Alzheimer’s disease and brain aging

    Journal of Neuroinflammation, Vol. 20, Núm. 1

  2. Pharmacological activation of insulin-degrading enzyme improves insulin secretion and glucose tolerance in diet-induced obese mice

    Diabetes, Obesity and Metabolism, Vol. 25, Núm. 11, pp. 3268-3278

2022

  1. Evolutionary Origin of Insulin-Degrading Enzyme and Its Subcellular Localization and Secretion Mechanism: A Study in Microglial Cells

    Cells, Vol. 11, Núm. 2

  2. Insulin-degrading enzyme ablation in mouse pancreatic alpha cells triggers cell proliferation, hyperplasia and glucagon secretion dysregulation

    Diabetologia, Vol. 65, Núm. 8, pp. 1375-1389

  3. Primary Cilia in Pancreatic β- and α-Cells: Time to Revisit the Role of Insulin-Degrading Enzyme

    Frontiers in Endocrinology, Vol. 13

2021

  1. Effects of fasting and feeding on transcriptional and posttranscriptional regulation of insulin‐degrading enzyme in mice

    Cells, Vol. 10, Núm. 9

  2. Fisiología del sistema endocrino: manual del estudiante

    Ediciones Universidad de Valladolid (EdUVa)

  3. Modulation of insulin sensitivity by insulin-degrading enzyme

    Biomedicines, Vol. 9, Núm. 1, pp. 1-38

  4. Retraction notice: Retraction notice to “Growth factors and beta cell replication” (International Journal of Biochemistry and Cell Biology (2007) 39(11) (2049–2062), (S1357272507001768), (10.1016/j.biocel.2007.05.023))

    International Journal of Biochemistry and Cell Biology

  5. miR-126 contributes to the epigenetic signature of diabetic vascular smooth muscle and enhances antirestenosis effects of Kv1.3 blockers

    Molecular Metabolism, Vol. 53

2020

  1. Assessment of Insulin Tolerance Ex Vivo

    Methods in molecular biology (Clifton, N.J.), Vol. 2128, pp. 291-300

  2. Assessment of Insulin Tolerance In Vivo in Mice

    Methods in molecular biology (Clifton, N.J.), Vol. 2128, pp. 217-224

  3. Hepatic insulin-degrading enzyme regulates glucose and insulin homeostasis in diet-induced obese mice

    Metabolism: Clinical and Experimental, Vol. 113

  4. Intestinal fructose and glucose metabolism in health and disease

    Nutrients, Vol. 12, Núm. 1

  5. Modulation of Glial Responses by Furanocembranolides: Leptolide Diminishes Microglial Inflammation in Vitro and Ameliorates Gliosis In Vivo in a Mouse Model of Obesity and Insulin Resistance

    Marine drugs, Vol. 18, Núm. 8

2019

  1. Manipulation of Transmembrane Transport by Synthetic K+ Ionophore Depsipeptides and Its Implications in Glucose-Stimulated Insulin Secretion in β-Cells

    Chemistry - A European Journal, Vol. 25, Núm. 39, pp. 9287-9294