IRENE
COZAR CASTELLANO
PROFESORES TITULARES DE UNIVERSIDAD
Publications (58) IRENE COZAR CASTELLANO publications
2023
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Insulin-degrading enzyme (IDE) as a modulator of microglial phenotypes in the context of Alzheimer’s disease and brain aging
Journal of Neuroinflammation, Vol. 20, Núm. 1
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Pharmacological activation of insulin-degrading enzyme improves insulin secretion and glucose tolerance in diet-induced obese mice
Diabetes, Obesity and Metabolism, Vol. 25, Núm. 11, pp. 3268-3278
2022
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Evolutionary Origin of Insulin-Degrading Enzyme and Its Subcellular Localization and Secretion Mechanism: A Study in Microglial Cells
Cells, Vol. 11, Núm. 2
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Insulin-degrading enzyme ablation in mouse pancreatic alpha cells triggers cell proliferation, hyperplasia and glucagon secretion dysregulation
Diabetologia, Vol. 65, Núm. 8, pp. 1375-1389
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Primary Cilia in Pancreatic β- and α-Cells: Time to Revisit the Role of Insulin-Degrading Enzyme
Frontiers in Endocrinology, Vol. 13
2021
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Effects of fasting and feeding on transcriptional and posttranscriptional regulation of insulin‐degrading enzyme in mice
Cells, Vol. 10, Núm. 9
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Fisiología del sistema endocrino: manual del estudiante
Ediciones Universidad de Valladolid (EdUVa)
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Modulation of insulin sensitivity by insulin-degrading enzyme
Biomedicines, Vol. 9, Núm. 1, pp. 1-38
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Retraction notice: Retraction notice to “Growth factors and beta cell replication” (International Journal of Biochemistry and Cell Biology (2007) 39(11) (2049–2062), (S1357272507001768), (10.1016/j.biocel.2007.05.023))
International Journal of Biochemistry and Cell Biology
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miR-126 contributes to the epigenetic signature of diabetic vascular smooth muscle and enhances antirestenosis effects of Kv1.3 blockers
Molecular Metabolism, Vol. 53
2020
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Assessment of Insulin Tolerance Ex Vivo
Methods in molecular biology (Clifton, N.J.), Vol. 2128, pp. 291-300
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Assessment of Insulin Tolerance In Vivo in Mice
Methods in molecular biology (Clifton, N.J.), Vol. 2128, pp. 217-224
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Hepatic insulin-degrading enzyme regulates glucose and insulin homeostasis in diet-induced obese mice
Metabolism: Clinical and Experimental, Vol. 113
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Intestinal fructose and glucose metabolism in health and disease
Nutrients, Vol. 12, Núm. 1
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Modulation of Glial Responses by Furanocembranolides: Leptolide Diminishes Microglial Inflammation in Vitro and Ameliorates Gliosis In Vivo in a Mouse Model of Obesity and Insulin Resistance
Marine drugs, Vol. 18, Núm. 8
2019
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Manipulation of Transmembrane Transport by Synthetic K+ Ionophore Depsipeptides and Its Implications in Glucose-Stimulated Insulin Secretion in β-Cells
Chemistry - A European Journal, Vol. 25, Núm. 39, pp. 9287-9294
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Pancreatic β-cell-specific deletion of insulin-degrading enzyme leads to dysregulated insulin secretion and β-cell functional immaturity
American journal of physiology. Endocrinology and metabolism, Vol. 317, Núm. 5, pp. E805-E819
2018
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Cembranoids from Eunicea sp. enhance insulin-producing cells proliferation
Tetrahedron, Vol. 74, Núm. 16, pp. 2056-2062
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Chloro-furanocembranolides from Leptogorgia sp. Improve pancreatic beta-cell proliferation
Marine Drugs, Vol. 16, Núm. 2