Publicaciones (19) Publicaciones de JAVIER CASAS REQUENA

2022

  1. Altered Surface Expression of Insulin-Degrading Enzyme on Monocytes and Lymphocytes from COVID-19 Patients Both at Diagnosis and after Hospital Discharge

    International Journal of Molecular Sciences, Vol. 23, Núm. 19

  2. PSTPIP1-LYP phosphatase interaction: structural basis and implications for autoinflammatory disorders

    Cellular and Molecular Life Sciences, Vol. 79, Núm. 2

  3. Phosphorylation of cPLA2 α at Ser505 Is Necessary for Its Translocation to PtdInsP2-Enriched Membranes

    Molecules, Vol. 27, Núm. 7

2021

  1. Lipin-1-derived diacylglycerol activates intracellular TRPC3 which is critical for inflammatory signaling

    Cellular and Molecular Life Sciences, Vol. 78, Núm. 24, pp. 8243-8260

2020

  1. Lck bound to coreceptor is less active than free Lck

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, Núm. 27, pp. 15809-15817

2018

  1. Regulation of phagocytosis in macrophages by membrane ethanolamine plasmalogens

    Frontiers in Immunology, Vol. 9, Núm. JUL

2014

  1. Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor

    Nature Communications, Vol. 5

  2. Protein kinase C-η controls CTLA-4-mediated regulatory T cell function

    Nature Immunology, Vol. 15, Núm. 5, pp. 465-472

2013

  1. Coreceptor affinity for MHC defines peptide specificity requirements for TCR interaction with coagonist peptide-MHC

    Journal of Experimental Medicine, Vol. 210, Núm. 9, pp. 1807-1821

  2. Themis sets the signal threshold for positive and negative selection in T-cell development

    Nature, Vol. 504, Núm. 7480, pp. 441-445

2011

  1. Initiation ofTCR phosphorylation and signal transduction

    Frontiers in Immunology, Vol. 2, Núm. DEC

  2. Protein kinase C η is required for T cell activationand homeostatic proliferation

    Science Signaling, Vol. 4, Núm. 202

2010

  1. The cationic cluster of group IVA phospholipase A 2 (Lys 488 /Lys 541 /Lys 543 /Lys 544) is involved in translocation of the enzyme to phagosomes in human macrophages

    Journal of Lipid Research, Vol. 51, Núm. 2, pp. 388-399

2009

  1. Lipid droplet biogenesis induced by stress involves triacylglycerol synthesis that depends on Group VIA phospholipase A2

    Journal of Biological Chemistry, Vol. 284, Núm. 9, pp. 5697-5708

  2. Requirement of JNK-mediated phosphorylation for translocation of group IVA phospholipase A2 to phagosomes in human macrophages

    Journal of Immunology, Vol. 183, Núm. 4, pp. 2767-2774

2008

  1. Group IVA phospholipase A2 is necessary for the biogenesis of lipid droplets

    Journal of Biological Chemistry, Vol. 283, Núm. 41, pp. 27369-27382

2007

  1. Group V phospholipase A2-derived lysophosphatidylcholine mediates cyclooxygenase-2 induction in lipopolysaccharide-stimulated macrophages

    Journal of Immunology, Vol. 179, Núm. 1, pp. 631-638

2006

  1. Overexpression of cytosolic group IVA phospholipase A2 protects cells from Ca2+-dependent death

    Journal of Biological Chemistry, Vol. 281, Núm. 9, pp. 6106-6116

  2. Phosphatidylinositol 4,5-bisphosphate anchors cytosolic group IVA phospholipase A2 to perinuclear membranes and decreases its calcium requirement for translocation in live cells

    Molecular Biology of the Cell, Vol. 17, Núm. 1, pp. 155-162