ChemInform Abstract: The Reaction of Carbanions from 3-Methyl-5-phenylisoxazole with Electrophilic Compounds.

  1. ALBEROLA, A. 1
  2. CALVO, L. 1
  3. RODRIGUEZ RODRIGUEZ, T. 1
  4. SANUDO, C. 1
  1. 1 Universidad de Valladolid
    info

    Universidad de Valladolid

    Valladolid, España

    ROR https://ror.org/01fvbaw18

Journal:
ChemInform

ISSN: 0931-7597

Year of publication: 2010

Volume: 23

Issue: 37

Pages: no-no

Type: Article

DOI: 10.1002/CHIN.199237183 GOOGLE SCHOLAR lock_openOpen access editor

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Abstract

The reaction of the title compound (I) with the electrophiles (II) is studied in the presence of different bases.When BuLi is used mixtures of the products (III) and (IV) are formed while LICA/TMEDA only leads to (III). In the presence of LICA the product distribution (III)/(IV) depends on the halide used for the reaction. The reaction of (I) with other electrophiles, e.g. (V), also proceeds regioselectively in the presence of LICA/TMEDA.

Bibliographic References

  • ALBEROLA, (1992), J. Heterocycl. Chem., 29, pp. 445, 10.1002/jhet.5570290225